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Structure-guided optimisation of NMR screen hit The successful soaking of NMR hit analogues 3032 into TRF1 TRFH crystals validated their site-specific binding and opened up an opportunity to design more analogues in silico

"Detoxification": what science describes and what "detox" distorts Hepatic detoxification relies on enzymes that transform fat-soluble molecules into more water-soluble forms, allowing for their elimination

The certainty of evidence was rated using the Grading of Recommendations Assessment, Development, and Evaluation approach, and risk of bias was assessed using Cochrane tool

A standard blood test for vitamin B12 can be misleading, especially if you've been taking high-dose B12 supplements

Additionally, radiation-induced ROS comprises not only peroxides but an array of other ROS such as hydroxyl, peroxyl, superoxide, and hydroperoxyl, among others, which add more complexity to the mechanism of radiation injury [36, 37]